@c3291393 Yes you can.
Check out the Send Mail Docs from SendGrid https://sendgrid.api-docs.io/v3.0/mail-send/v3-mail-send
You will need to upload the file, get the URL of the file and then use nodejs-base64-encode (NPM) to encode the URL of the file inside a request.get() function using the request-promise NPM.
Use the SendGrid NPM example (link provided by @givemeawhisky in the above comments)